Role Of Anaesthetist In Sedation For Diagnostic Procedures : The Glass Is Half Empty ? A Narrative Review

Sedation of outpatients undergoing diagnostic and therapeutic procedures remains a controversial topic, and there remains a paucity of literature and guidelines to help inform sound clinical decisions. As these are frequently performed procedures that offer advantages to patients in terms of their comfort and well-being, we aimed to better address this information deficit and to clarify why appropriate guidelines are still not available. To this end, we propose reviewing sedation procedures performed using Magnetic Resonance Imaging (MRI) in pediatric patients.


Introduction
Sedation of outpatients undergoing diagnostic and therapeutic procedures remains controversial.Despite the increase in the last few years in the number and complexity of such outpatient procedures, there is limited scientific data and no guidelines to help describe safe, optimal sedation.The few scientific publications on procedural sedation address such things as standardization of processes and reasons for sedation [1][2][3][4][5].Given the frequency and importance of these procedures in terms of the comfort and well-being of patients, we have decided to review the literature with the goal of establishing the reason(s) that "appropriate" guidelines have thus far not been issued.
Our analysis has concentrated on sedation procedures performed to facilitate diagnostic procedures like Magnetic Resonance Imaging (MRI), Computerized Tomography (CT scans) etc., in pediatric patients.Following this analysis we have tried, briefly, to suggest some solutions that could aid the formulation of 3.There is no agreement on the utilization and validity of various measurement scales that evaluate the phases of sedation [13].
The "technical-organizational" issues have emerged in the last few years due to a geometrical increase of the number of requests for sedation and their associated costs.An increased number of procedures has produced an increased demand for anesthetists that has resulted in substantially increased costs for these procedures.In order to meet demand but still contain costs, a compromise solution has taken root.This compromise consists of allowing medical personnel not trained in anesthesiology to administer sedative drugs [5,7,11,14].Furthermore, in recent years, some countries have given permission to nurses, paramedics, and other healthcare professionals to administer sedatives.In our opinion, this has increased the number of scientific-clinical issues.
As a result, the attention of the researchers on the topic of sedation has been diverted from the procedure itself.Some studies have been designed to establish who, among the healthcare personnel, can appropriately deliver sedative drugs, which drugs to use and their route of administration in various procedures.This shift between the above-mentioned issues has favoured the technical-organizational rather than the scientificclinical issue [5,15,16].This choice by researchers has brought more confusion and variability to the available published data and makes them difficult to compare.Indeed, these data have been produced by different healthcare professionals utilizing different techniques.Some of them have different skills in the management of the airways, depth of sedation, hemodynamic derangement caused by drugs, and overall protection of the sedated patient [5,11,12,[15][16][17][18].
During a sedation procedure (where the main objective is to achieve the patient's immobility and, in some cases, deep analgesia) the level of confidence/experience of the operator in the utilization of sedative and analgesic drugs, together with knowledge of drug actions is crucial to patient safety; this should be the basic standard used in the future to compare techniques, drugs and modes of administration in sedative procedures [5,11,12,[15][16][17][18]. Some studies (and indeed routine clinical practice) do not always specify minimum required skills for the healthcare professional delivering sedation, and in some cases, even anesthesia may be administered by someone other than a trained and skilled anesthetist.As a result, it could be argued that some drugs and techniques have not been optimally employed [5,11,12,[14][15][16][17][18].This argument is further supported by the fact that in multiple papers, complications associated with sedative procedures have been described, which necessitated help from an anesthetist [5,11,12,[14][15][16][17][18].
Even when well-trained healthcare professionals are used, their lack of specific training and experience in sedation may well have affected the results of various studies [5,11,12,[14][15][16]18].

Proposal for Solution
Robust guidelines must be based on sound medical evidence, which in this case can only be obtained by standardizing how sedation is delivered.The optimal delivery of sedation is accomplished by clinician strained in anesthesia.Their experience would allow them to identify and utilize the best available drugs and techniques to full potential to obtain the optimal outcome [6][7][8]10,12,15,19,20].This would enhance patient safety and also result in studies yielding data with comparable methodologies, skills, and techniques.
Concerning the problems about the sedation evaluation scales, we support the indications of Williams and collaborators13.The authors, after careful comparison and analysis of various sedation measurement scales, point out that, until now, there has been a lack consistency among various validation tools used during before, during, and after procedures.The Ramsay score 21has been recommended; itis a well-known and frequently applied scoring system, used for documentation of adequate depth of sedation [7,13,20,22].
In the domain of clinical and sedation efficacy/quality, the satisfaction of the physician performing the procedure must be assessed in addition to the clinician who deliversthe sedation.The literature seems to indicate that, for example, the result of sedation for anMRI scan could be evaluated/graded for quality on a 3-point scale: (i) excellent quality, that is, no motion artifact; (ii) minor motion, scan completed; or (iii) major motion; scan incomplete [18].
For documentation of adequate recovery after the procedure, it the wide spread Modified Aldrete score 23 used for determination of discharge criteria could be applied 12-13,22.Detection of an emergence delirium could also be performed with the Pediatric Anesthesia Emergence Delirium (PAED) scale during recovery time for a better understanding prolonged emergence [17,24,25].

Discussion
Two parallel conditions describe the situation in which outpatient sedation is currently administered: more and more, non-anesthesiologists are administering outpatient sedation and there remains a paucity of literature and no guidelines to advise them as to the appropriate protocols.These two trends are inter-related.The use of non-anesthesiologists to administer and manage outpatient sedation often means that drugs and techniques may vary widely among institutions (and even within an institution) and may not always represent the optimized use of the available agents and methods.As a result, studies of outpatient sedation yield data that are difficult to compare because different facilities use different drugs, different routes of administration, and so on, for the same procedures.Without comparable data on which to draw conclusions, arriving at scientifically sound guidelines is nearly impossible.Our study, which was based on studies limited to the field of pediatric diagnostic imaging procedures, shows what we think is a trend across all fields of outpatient procedures.Non-anesthesiologists often administer

Role Of Anaesthetist In Sedation For Diagnostic Procedures: The Glass Is Half Empty? A Narrative Review
Copyright: © 2017 Alberto P, et al.
outpatient sedation and currently drugs, techniques, and routes of administration vary so widely that robust data for guidelines simply are not available.
Although it may seem difficult to remedy, it is easy to understand how this situation arose.Outpatient procedures have increased markedly in recent years; they are generally more economical than inpatient procedures and patients tend to prefer the convenience of day surgery.Outpatient procedures make financial sense for providers, clinics, payers, and patients.Patients like them and they facilitate the all-important daily logistics of a busy clinic.With this sudden surge in in-patient procedures came an increased demand for those who could administer sedation in the outpatient setting.It seems more cost efficient to utilize the services of a non-anesthesiologist, and there is even some support for this approach.Certain healthcare professionals could reasonably be trained to administer sedation in the outpatient setting and the use of these non-anesthesiologist as been effective in containing costs.The problem arises that these healthcare professionals would likely not be as well informed about sedative agents, analgesics, and sedation techniques as an anesthesiologist; in the event of complications or a difficult case, these healthcare professionals might lack the appropriate skills to manage a crisis.This problem might be at least somewhat ameliorated by the existence of clear evidence-based guidelines on outpatient sedation.However, our current state of haphazard protocols (different healthcare professionals administer outpatient sedation in different ways at different institutions) has hampered our ability to capture reasonable and reliable data that can aid in the formulation of such guidelines.
We advocate that outpatient procedures rely on the services of anesthesiologists and these specialists work together to use the same validated measurement tools to quantify sedation levels and determine discharge criteria.These specialists should publish their work to contribute to a body of literature that can be used to better define protocols and set up guidelines for outpatient sedation.The experience and expertise of anesthesiologists is urgently needed so that these guidelines can be defined.This is not a clinical nicety, it is necessary to guard patient safety.

Conclusion
The recent rise in outpatient procedures has resulted in two trends: non-anesthesiologists frequently administer outpatient sedation in these settings and there is limited literature and no guidelines to help determine these protocols.In our limited study of outpatient sedation involving pediatric patients undergoing imaging procedures, we defined clinical and technical obstacles to outpatient anesthesia and we advocate for the use of anesthesiologists to administer outpatient sedation as well as to use validated measurement tools and publish their findings.This would provide the foundation for the publication of scientifically sound evidence-based guidelines on outpatient sedation.