Dr. Ouchi’s laboratory investigates mechanisms of human carcinogenesis using series of transgenic/knockout mouse model. His group also studies stem cell/differentiation program. Approaches of the research include Cancel Biology, Systems Biology and Genomics.
Project 1: BRCA1/ATM Pathway and BRAT1 Function in Carcinogenesis
Project 2: Mechanisms of Differentiation from Hematopoietic Stem Cells
Project 3: Small Compound Application for Mouse Model of Human Cancer
Project 4: Genome Methylation Associated Regulation of Transcription
Project 5: Novel Metabolism Regulation in Cell-Cell Contact and Differentiation
Study biological function of BRCA1/ATM-associated BRAT1 protein.
Study Roles of DNA stress response proteins in the programmed iPS differentiation