Journal of Clinical Trials in Cardiology

Dr. Nicholas J. Ruggiero II, MD, FACP, FACC, FSCAI, FSVM, FCPP was born in Wilkes-Barre, PA. He graduated summa cum laude from King’s College in Wilkes Barre, PA with a major in Biology and minor in Molecular Genetics. He was awarded the prestigious Regina Award given to the graduating senior with the highest GPA in the Sciences. He then attended Jefferson Medical College where he graduated Magna Cum Laude and was awarded the Joseph Rogers Award, given to the senior student who best exemplifies a Jefferson physician. He performed his internship and residency in internal medicine at Thomas Jefferson University Hospital, where he received the resident teaching award twice and served as chief medical resident. He was awarded upon finishing his fellowship the Gregory Braden MD award, given to the top graduating interventional cardiology fellow in the country from the Society of Coronary Angiography and Intervention. He was recruited back to Jefferson to begin his own section in cardiology as the Director of Structural heart disease and non-coronary interventions. He is also the head of the TAVR program and the Jefferson Heart Institute Vascular Laboratory. He has published over 35 papers, authored numerous book chapters and abstracts, delivered multiple lectures and served on many national and international committees. He is board certified in internal medicine, cardiology, echocardiography, nuclear cardiology and interventional cardiology. He is a fellow of the ACP, ACC, SCAI, SVM and Philadelphia College of Physicians. He is currently at the rank of assistant professor at Jefferson Medical College and is the PI of multiple research trials.

Clinical Trials Dealing with Coronary, Peripheral and Structural Heart Interventions.

Rongli Zhang is currently a research scientist and serves as the director of Cardiovascular Physiology and Phenotype Labat Case Western Reserve University. He received his Ph.D. from China Academy of Chinese Medical Science in 2003, after his postdoctoral training at Tsinghua University. His work focuses on Cardiovascular Physiology using state-of-the-art animal models for basic and Translational Medicine Research. Robust and reliable disease models related to Cardiovascular, Urinary, and Central Nervous System have been established.  These models include, but are not limited to, Transverse aortic constriction, Myocardial infarction, Myocardial Ischemia/Reperfusion Injury, Heart failure,middle cerebral artery occlusion, kidney ischemia/reperfusion injury. He closely collaborates with investigators from Case Cardiovascular Research Institute, Institute for Transformative Molecular Medicine and Harrington Heart & Vascular Institute to bring together researchers of multiple disciplines to link physiologic and pathologic function at the in vivo.

Cardiovascular Physiology Using  State-of-Art Murine Models for Basic and Translational Medicine Research, Robust and Reliable Disease Models Related to Cardiovascular, Urinary, and Central Nervous System, Transverse Aortic Constriction (TAC), Myocardial Infarction, Myocardial Ischemia/Reperfusion injury, Heart Failure, Limb Ischemia, Middle Cerebral Artery Occlusion (MCAO), Kidney Ischemia/Reperfusion Injury, Deep Vein Thrombosis.  

Dr. Xuejun Parsons obtained her PhD in Biochemistry, Molecular & Cell Biology from Cornell University in 1998, and completed her PostDoc studies as a Leukemia and Lymphoma Society Research Fellow at University of California, San Diego, in 2002. Since, she has been supported by grants from National Institutes of Health to become an independent investigator and leader in human embryonic stem cell research. She is the Co-Founder and President of San Diego Regenerative Medicine Institute (http://www.SDRMI.org), Founder & CEO of Xcelthera (http://www.Xcelthera.com), and Founder of California Consortium for Regenerative Medicine StartUp.

Human Stem Cell Research, Stem Cell Therapy, Regenerative Medicine, Neural and Cardiac Regeneration, Stem Cell Genomics, Tissue Engineering.

Dr.Carlos A Labarrere is a Senior Scientist whose research focused on Vascular Biology and Immunopathology of Atherosclerosis and Atherosclerosis-like lesions following Solid organ Transplantation and Pregnancy. He had a broad background in Pathology and Immunopathology. He is a pioneer in studies related to the detection of early Biomarkers of coagulation and endothelial activation/inflammation for Cardiac Allograft Vasculopathy (CAV), the transplant-associated form of Atherosclerosis. 
His investigations have led to changes in the criteria used by the ISHLT to evaluate Antibody-Mediated Rejection (AMR).

 He had demonstrated a solid record of accomplishing numerous research projects in areas of Placental Research and Heart Transplantation Research. His investigations impact an area of high relevance for the heart transplant population—an area recently recognized by a NHLBI working group as a key area for cardiac transplantation research.

Cardiovascular Research, Clinical Research, Heart Transplantation Research, Pathology, Immunopathology, Transplantation, Atherosclerosis, Preeclampsia, Intrauterine Growth Restriction, Biomarkers, Innate Immunity, Chronic Rejection, Cardiac Allograft Vasculopathy (CAV).

Gary E Meyerrose is a full professor in the Cardiology division at Texas Tech. He has been board certified in Cardiovascular in 1997 and recertified in 2005. He treats patients with heart attacks and Peripheral Vascular Disease. He is familiar with the risk factors that predispose to the development of atherosclerosis. He has been involved in previous studies dealing with various aspects of atherosclerotic vascular disease. 

Internal Medicine, Nuclear Medicine, Geriatric Medicine, and Cardiovascular Medicine and has Special Interest in Taking Care of Patients with Atherosclerotic Cardiovascular Disease.

Adel Khalifa Sultan Hamad is Consultant cardiologist and Bahrain first Cardiac Electro Physiologist at Mohammed bin Khalifa bin Salman Al Khalifa Cardiac Centre (Bahrain Defence Force Hospital). He is Board certified in internal medicine and adult cardiology from University of Toronto, Canada. Subsequently he did a postdoctoral fellowship in Cardiac Electrophysiology at Toronto General Hospital. During his cardiology residency he did a research focusing on the “Spatial organization of ventricular fibrillation in explanted Langendorff human heart” which he presented in the Annual Ursula Bangs Clinical and Research day. Current practice ranges from device implant (pacemakers, ICDs and CRTs) to performing electrophysiology studies and ablation of various arrhythmias. Currently, he is the president of the Gulf Heart Rhythm Society (GHRS). He is a member of various societies including Bahrain Medical Society, European Society of Cardiology, European Heart Rhythm Association and Heart Rhythm Society. He has many publications in local and international journals.

Cardiac Electrophysiologist, Specialized in Arrhythmia Diagnosis and Management.

Dr. Yiru Guo is presently a faculty and Professor of Medicine and the Director of Murine Research Laboratoryat the University of Louisville, Louisville, KY, USA. He has published seminal papers in the field of cardioprotection, especially in the ischemic preconditioning, gene cell therapy. He has published over 60 peer-reviewed publications, 90 abstracts and presented lectures nationally and internationally on American Heart Association (AHA), Scientific Session; World Congress of International Society for Heart Research (ISHR). Dr. Guo is a Fellow of the American Heart Association (FAHA). Dr. Guo is currently supported by seven NIH grants including one where he serves as PI.

Elucidating the Mechanisms of Ischemic-Pharmacologic and Exercise-Induced Preconditioning by Using the Ischemia/Reperfusion in Vivo Model in Genetically Engineered Animals, Protection of Ischemic Myocardium by Using Gene and/or Cell Therapy, Elucidating Adaptations to Ischemia/Reperfusion Injury in the Aging Heart, and Using Adult Stem Cell to Repair Damage Heart.

Sonia Regina Jurado has graduated in Biological Sciences from the State University of Rio de Janeiro (1995), master in Morphology from the State University of Rio de Janeiro (1998) and Ph.D. in Pathophysiology in Clinical Medicine from the Universidade Estadual Paulista Julio de Mesquita Filho (2005),  Brazil.  She is an Associate professor in the Nursing Course at the Federal University of Mato Grosso do Sul (UFMS) and tutor group Tutorial Education in Nursing/UFMS, Brazil. Prof. Jurado has experience in the area of Medicine, Nursing and Biology. She has published papers in scientific journals and  presented papers in conferences. She has an interest in research in Public Health, with emphasis one epidemiology and chronic diseases. 

Congenital Heart Disease, Hypertension Maternal Effectson Fetal Development, Hypertension and Heart Diseaseand Vascular Disorders.

Syed Aitizaz Uddin was Consultant Incharge of Cardiac Surgery section of North West Armed Forces Hospital,Tabuk, Saudi Arabia for last 8 years. Track record as operating surgeon of more than 1500 Adult Cardiac Operations. Including emergency and salvage procedures redo operations, Total Arterial Revascularization, OPCAB surgery, complex valve repairs and multiple valves replacements. Involved as a trainee in cardiac and pulmonary transplant and adult ECMO and VAD management in UK and Canada. Strong Training back ground in Congenital Heart Surgery as a Senior Registrar in Prince Sultan Cardiac Center Riyadh and then as a Fellow in Boston Children’s Hospital and Cincinnati Children’s Hospital Medical Centre,USA. Established the Congenital Heart Surgery Program at NWAFH Tabuk. Operating regularly neonates, infants and children for a variety of Congenital Cardiovascular malformations with complexity ranging from RACHAS group 1 to 5. Experience of more than 1000 Pediatric cardiac operations as a consultant cardiac surgeon. Good experience of chest trauma surgery, esophageal surgery and VATS procedures. Extensive experience in Cardiac Surgical Intensive care in both adult and congenital heart cases. Involved in clinical research and training of Residents and Registrars in cardiac surgery. Supervised PhD Thesis of one Perfusionist in our department. Three Registrars trained directly under my supervision in Tabuk are now working as consultant cardiac Surgeons in Saudi Arabia, Canada and Egypt.

Ventricular Diastolic Function, Pathophysiology of Extracorporeal Circulation, Risk Scoring and Outcome Analysis in Adult and Congenital Cardiac Surgery.
 

Dr. Alejandro Barbagelata born and raised in Argentina, medical degree at the University of Buenos Aires, Argentina. Residency/Cardiology Fellowship at the worlwide renowned Favaloro Foundation in Buenos Aires, Argentina. Cardiac cath/intervention at the Sanatorio Guemes under Dr Dela Fuente. International scholar in artificial organs at the Cleveland Clinic in 1990 and Duke Clinical Research Institute Research Fellow in Clinical Trails under Robert Califf mentorship 1992-1994. Instrumental in establishing the first international Latino version of the Duke Databank for cardiovascular diseases in the Favaloro Institute in Argentina. Member of the Cardiology Division at the University of Texas Medical Branch since March 2005 as a CCU and cardiac cath lab attending (invasive cardiologist) in all type of cardiovascular diseases with stronger focus in Advance Heart Failure /Cardiogenic Shock. Helped to establish a advanced heart failure fellowship program with currently 3 fellows/year, Advanced Heart failure clinic and devices in Heart failure both percutaneous such as aquapheresis, 2.5 impella, Cardiac power 3.5-4lt Abiomed, and surgical such as being part of the approval team for destination therapy on HM II. UNOS Director of Heart failure and Transplant Medicine.

Acute MI, Advanced Heart Failure, Assist Devices, Cardiovascular diseases.

After obtaining Master’s degree in Physics (Electronics) and PG Diploma and M.Tech in E&C Eng. Prof. Singh joined university of Roorkee as SRF and completed his Ph. D research work in 1980. He later joined CSIR as Sr. Scientist and rose to the position of Chief Scientist, Head of Biomedical Division, Head of Electrical Standards and Measurements and Project Advisor at National Physical Laboratory New Delhi. Prof. Singh has to his credit about 50 research publications in National and International Journals of repute and conferences. He had been the Principal Investigator of a number of Govt. Of India sponsored research projects and some of his international research and products invited international recognition and applause by media and dignitaries including Prime Minister and President of India. Besides, he is associated with several International Journals as Hon. Editorial Board Member and Peer Reviewer. He was offered Thomson Foundation Scholarship UK in 1978 and also invited by university of Krakow Poland, to start a collaborative program on Thin-film integrated devices. He was also invited by Griffith University Australia as visiting scientist and Visiting Fellow by Cheju University South Korea. One of his publications and similar talk delivered at University of Westminster London and at ICMCC council Netherland was selected among best five publications in the subject domain by Bio-Med library USA. Prof. Singh is a fellow of IETE and had been on the Delhi College of Engineering faculty list as visiting faculty apart from being associated with several technical boards, engineering colleges and universities to evaluate their R&D projects and other technical programs. He visited several countries and universities for delivering invited lectures and chairing sessions in International conferences. Recently he was invited by Cardiology 2013 Society America to deliver invited talk and subsequently appointed as member of organizing committee to hold world congress on Cardiology 2014 in USA. He was also invited by Cancer and Cell Therapy USA to present his work on Cancer detection. He was also invited by International journal on Electro chemical as Guest Editor. He was associated with RGGI Meerut as Director for one year. He had been with JBIT Dehradun as Advisor. His work on voice activated devices and robotics has got international recognition. He had been associated with Drona college of Engineering Dehradun as Director for three years. Presently he is associated with R D Engineering College NCR as Director General.      

Cardio-vascular Signal Detection, Monitoring, Analysis and Transmission, Cancer Module Detection, Speech Synthesis, Bio-Medical Signal Processing, Robotics and its Social Applications, Design and Development of Aids and Appliances for disabled.  

Dr. Marwan M. Refaat is an Assistant Professor of Medicine in the departments of Internal Medicine, Biochemistry and Molecular Biology at the American University of Beirut Faculty of Medicine. He is board certified in Internal Medicine, Cardiovascular Medicine, Cardiac Echocardiography and Clinical Cardiac Electrophysiology. He was inducted for membership to the Alpha Omega Alpha Honor Medical Society as a medical student and was a recipient of many awards including the Alpha Omega Alpha Medical Student Research Award (2002), the American College of Physicians Research Award (2004), Massachusetts Medical Society Annual Research Award (2007), Massachusetts General Hospital Department of Medicine Award (2007), University of Pittsburgh Department of Medicine Best Research Award (2008 and 2009), American Heart Association Great Rivers Affiliate Research Award (2008), University of Pittsburgh Medical Center Ziady Memorial Award for Outstanding Achievement in the Care of the Cardiac Patient (2010), Massachusetts Institute of Technology Arab Students’ Organization Science and Technology Young Professional Achievement Award (2011) and the 2011-2012 Heart Rhythm Society Kenneth M. Rosen Fellowship Award in Cardiac Pacing and Electrophysiology. He has more than 35 manuscripts in peer-reviewed journals.

Implantation of Pacemakers/Defibrillators, Lead Management and in Ablation of Complex Arrhythmias including Atrial fibrillation and Ventricular Arrhythmias.

Professor Malcolm John Underwood obtained his MB ChB from the University of Leicester in 1987 and subsequently his FRCS from the Royal College of Surgeons of Edinburgh in 1991. This was followed by a Doctorate of Medicine in 1994 and FRCS (CTh) four years later. His contributions led to him being awarded The Ronald Edwards Medal by the Society of Cardiothoracic Surgeons of Great Britain and Ireland in 1993; and The Cardiac Research Club Prize for 1992 and 1993.In 1997, he was further awarded several other prizes, most prestigious, the Francis Fontan Prize from the European Association of Cardiothoracic Surgeons for an International Clinical Fellowship in the Department of Cardiothoracic Surgery, St Luc Hospital Brussels along with a Research Fellowship from the University of Louvain (Brussels), and a travelling scholarship from the Royal College of Surgeons, Edinburgh. He has been a Consultant in Cardiothoracic Surgery for nearly 15 years and was appointed as Senior Lecturer/Consultant Cardiothoracic Surgeon at the Bristol Heart Institute in 1999 and subsequently NHS Consultant in Cardiothoracic Surgery at the Bristol Royal Infirmary from 2002. In 2005 he was appointed as Head of Cardiac Surgery at the Chinese University of Hong Kong (CUHK) and in 2007 as Chief, Division of Cardiothoracic Surgery, CUHK, Prince of Wales Hospital, Hong Kong. In 2012 he was awarded the Distinguished Surgeon Award from the College of Surgeons of Singapore to reflect his contribution to advancement of surgery there. In addition, Professor Underwood is past-Chairman of Specialty Group in Cardiothoracic Surgery, Hong Kong, Chairman of the Cardiothoracic Board, the College of Surgeons of Hong Kong and is Professor, Division of Cardiothoracic Surgery at the Chinese University of Hong Kong.

Centered on Valvular Surgery, Valve Repair, Aortic Surgery, Clinical Audit and Training.

Dr. Sanjeev Saxena graduated from the University of Georgia, cum laude, with a bachelors of science degree in Biology. He received his doctorate in medicine from the Medical College of Georgia, in Augusta, GA. While he was at Penn State, he was accepted into the prestigious Cardiovascular Medicine fellowship at the University of Miami/Jackson Memorial Medical Center and affiliated hospitals. He has been an instructor in Cardiovascular disease at the University of Miami School of Medicine's Medical Training and Simulation Lab, as well as the course director for the Cardiology training for Miami-Dade Community College Physician Assistant program.
During his residency, he won a national award from the American College of Physicians for original clinical research in the area of Cardiovascular disease.

Medial Device Therapy in the Management of Advanced Heart Failure Role of Vascular Endothelial Dysfunction in Venous Insufficiency Community Education in Sudden Cardiac Death.

Dr. Raj Janardhanan joined University of Arizona’s Department of Medicine as an Associate Professor of Medicine. He is the Director of Non-Invasive Cardiac Imaging at the University of Arizona Medical Center South Campus. He is a member of the Sarver Heart Center as well as the Co-Director of Non-Invasive Cardiac Imaging at the University Campus. After completion of the Membership of the Royal College of Physicians (MRCP) diploma, he chose to move to the US in 2004 when he was offered the position of Clinical Project Director of the Echocore lab at the Brigham and Womens’ Hospital, Harvard University to work with the renowned Dr Marc Pfeffer and Scott Solomon. He has published seminal papers in the field of myocardial contrast echocardiography. His publications include several peer reviewed articles and book chapters which are available on pubmed. He is a Fellow of the American College of Cardiology (FACC). He is fully certified in echocardiography with a Diplomate in Adult Comprehensive Echocardiography as well as Fellowship of the American Society of Echocardiography (FASE). This is the highest level of recognition in the field of Echocardiography.

3-Dimensional Echocardiography, Special Interest in Imaging in Structural Heart Disease and Interventional 3D-TEE During Transcatheter and Intra-Operative Procedures.

Dr. Toomas Sarev trained in Medicine at Tartu University, Estonia 1988. He did his training in Cardiology at Tampere University Hospital, Finland. He worked 2002-2010 as an Interventional Cardiologist at Karolinska and Danderyd Univ Hospitals in Stockholm, Sweden. He worked for four months at the Salam Centre of Cardiovascular Surgery, Khartoum, Sudan.

Transradial PCI, Invasive Hemodynamics, Pressure Wire Measurements, IVUS, Rotational Atherectomy, Invasive Hemodynamics, Interventional Cardiology.

Dr. Miltiadis Papalexandris, MD, PhD (c) was born in Athens, Greece and his training includes: Residency at the Naval & Veterans Hospital in Athens (internal medicine) Greece, Residency in Germany at the Waldbröl KH, Teaching Hospital of University of Bonn and at the Stadtische Kliniken Neuss, Teaching Hospital of University of Dusseldorf (Cardiology). Research Fellowship about new stent technologies, especially concerning the endothelial progenitor cell capture stents in STEMI. He is the co-author of the PCR-EAPCI text book about the percutaneous Interventional Cardiovascular medicine from the European Society of Cardiology. He is a member of the European and German Society of Cardiology, German Society of Intensive/Critical Care and member of the EAPCI. He is currently working at the Städtische Kliniken Neuss, Teaching Hospital of the University of Düsseldorf, Germany.

Thrombotic Events after Coronary Interventions, Optimal Antiplatelet Therapy Post Angioplasty, Percutaneous Approach in the Treatment of Structural Heart Disease, Intravascular Imaging, and Critical & Intensive Care in Cardiology.

 Dr. Marjan Boshev currently works at the Department for Invasive and Interventional Cardiology, University Clinic of Cardiology, Skopje, Macedonia as a youngest Interventional Cardiologist. He started in 2006 to perform Coronary Angiography and Percutaneous Coronary Interventions (PCI) via transfemoral approach, but soon he had switched to so-called wrist-approach (transradial and transulnar approach), His exclusive vascular approach (more than 95%) is wrist approach (radial or ulnar), and very few patients undergo femoral approach, is high-volume center for PCI. In 2010 he had successfully finished 3 modules of the Interventional Cardiology Fellowship Program in Crossroads Institute, Brussels, Belgium. He is a professional educator in a few projects covered by our Ministry of Health. He is a author and co-author of many publications in domestic and international journals. He is a member of many associations like Macedonian Society of Cardiology, European Society of Cardiology (ESC), EAPCI, HFA of the ESC, Acute Cardiovascular Care Association etc.

PCI techniques, Novel Stent Technologies, Clinical and Comparative (cardiology) drug research, High Sensitivity Markers for Acute Myocardial Infarction, Markers of Vascular Wall Inflammation.

Dr. Rasha Ammar completed her graduation from faculty of Medicine, Cairo University in 1994, appointed as resident of Pediatrics in 1996 and as assistant lecturer of Pediatrics in 1998, promoted all the way. Her current position is Professor of Pediatrics and Pediatric Cardiology from 2013. From 2007 to 2011, she worked as Deputy Director of Cairo University Children's hospital. She joined the Pediatric Cardiology department since 1998 and as primary operator in the echo suite and cath lab from 2002 as post doctorate. Both her Master thesis and MD thesis were in Pediatric Cardiomyopathy. It was her great motivation to co- found the CM clinic in Cairo University Children's Hospital in 2003. She has been working as consultant in the clinic ever since and produced a number of research papers in the field. As a primary operator in Cardiac Cath Lab since 2002, she has great experience in Diagnostic and Hemodynamic assessment techniques as well as Interventional Cardiac Catheterization procedures in Pediatrics and in Adult structural heart disease. Her research papers include device closure, Cardiac Interventions, Molecular and Stem cell research and Cardiomyopathies.

Pediatric Cardiology, Interventional Catheterization, Heart Failure, Congenital Heart Disease, Adult Congenital Heart Disease, Cardiomyopathy, Molecular and Genetic Cardiology.

After receiving his Ph.D. in Microbiology and Immunology from The University of Texas Medical Branch in Galveston, Texas, Dr. Enrico A Duru completed postdoctoral fellowships at The University of Texas South western Medical Center, where his research endeavors focused on anti-HIV-1 vaccine development and Molecular Cardiology, and at The University of Alabama at Birmingham, where his research focused on HIV-1 infection kinetics and neutralizing antibody studies. He continued his biomedical research studies at The University of Texas Medical Branch at Galveston, where his work concentrated on the roles of G-protein-coupled signal transducers in allergic asthma and the modulation of immune responses in airway hyper responsiveness. Dr. Duru has been with the Vascular Biology and Therapeutics Program of The Department of Cardiovascular Surgery at The Houston Methodist Hospital Research Institute since 2009.

Anti-HIV-1 Vaccine Development ,HIV-1 Infection Kinetics and Neutralizing Antibody Studies, Molecular Cardiology and with the Vascular Biology and Therapeutics Program.

Dr. Luis Daniel Umezawa Makikadohas graduated in Medicine from Universidad Peruana Cayetano Heredia. Afterwards, moved to Madrid, Spain where he completed a five-year Critical Care Medicine residency program at Hospital Universitario 12 de Octubre de Madrid and an Associate degree in Medicine from Universidad Complutense de Madrid. He is an Attending Physician in Clínica Ricardo Palma. He has published papers in scientific journals and presented papers in conferences. He has an interest in research in critical care, with emphasis in extracorporeal life support and nutrition.

Critical Care Medicine, ECMO (Extracorporeal Membrane Oxygenation) Cardio Pulmonary Support in Critical Care, Nutrition, Transfusion Medicine.

Dr. Ahmed Elminshawy is the Head of Cardiothoracic Surgery Department, He is a Chief of Pediatric Cardiac Surgery Unit, Assiut university children's hospital and
Professor of Department of Cardiothoracic Surgery, Faculty of Medicine, Assiut University, Assiut, Egypt. He is also a Consultant Cardiothoracic surgeon, Assiut University Hospitals.

Neonatal Cardiac Surgery, Arterial Switch Operation, Single Ventricle Management.

Dr. Mahboob Alam is an Assistant Professor Medicine, Baylor College of Medicine, Houston, TX, Member, Professional Staff, Texas Heart Institute, Houston, TX, Director, Interventional Cardiology, Baylor Heart Clinic, Director, Interventional Cardiology Research, Baylor Heart Clinic, Member Editorial Board on several journals, Reviewer for several high impact Cardiology Journals (including JAMA, JACC, AJC, Journal of Interventional Cardiology, CCI etc.), More than 40 peer reviewed publications. Several in progress, More than 50 abstracts, presentations etc., Primary Investigator at Baylor College of Medicine for NIH funded CiRT clinical trial (Cardiovascular Inflammation Reduction Trial), Also, co-investigator on various ongoing clinical trials, Proficient in Biostatistics, Epidemiology, Outcomes Research and Meta-Analyses/Meta-Regression.

Acute Coronary Syndrome, Hypertrophic Obstructive Cardiomyopathy, Coronary Artery Disease, Peripheral Vascular Disease, Clinical Outcomes Research, Valvular Heart Disease.

Dr. Giuseppe Biondi Zoccai was born in San Remo, Italy. He obtained his MD diploma magna cum laude at the University Of Milan, Italy, in 1999 with a thesis on the comparison of diagnostic accuracy of different imaging tests for Takayasu arteritis. He completed compulsory military service in 2000 as Medical Officer in the 183rd Parachute Regiment of the Italian Army in Pistoia, Italy. He then pursued specialist training in cardiovascular medicine, obtaining his Cardiologist diploma magna cum laude at the Catholic University, Rome, Italy, in 2004 with a thesis on a systematic review and meta-regression focusing on the early invasive management of acute coronary syndromes. In 2004-2005 he completed a fellowship in interventional cardiology at the Invasive Cardiology Unit of St. Raffaele University Hospital, Milan, Italy. He worked as consultant cardiologist in the Cardiovascular Interventions Service of St. Donato Hospital, St. Donato, and of Abano Terme Hospital, Abano Terme, both in Italy. Since 2006 he has served as Assistant Professor, until 2010 in the Division of Cardiology of the University of Turin, Turin, Italy. During 2011 in the Division of Cardiology of the University of Modena and Reggio Emilia, Modena, Italy, and since late 2011 in the Department of Medico-Surgical Sciences and Biotechnologies of the Sapienza University of Rome, Latina, Italy, where he is currently involved in both noninvasive and invasive cardiology, as well as clinical research.He has published over 500 papers, authored numerous book chapters and abstracts, delivered multiple lectures and served on many national and international committees.

Advanced Biostatistical Methods, Evidence Based Medicine in Cardiology, Intracoronary Stents and the Impact of Inflammation in Heart Disease, Cardiovascular Disease, Endovascular Therapy and Meta-analysis.

Dr. Manikandan Panchatcharam is an Assistant Professor in the Department of Cellular Biology and Anatomy - Internal Medicine, Louisiana State University Health Sciences Center-Shreveport. Dr. Panchatcharam completed his MSc and PhD training in India. His postdoctoral training in cardiovascular biology was completed at the University of North Carolina –Chapel Hill. His particular interest is the hypothesis that mitochondria act as metabolic sensors that communicate with the nucleus through redox-dependent signaling pathways. His current work involves establishing a cell culture model to investigate the consequences of sub-lethal mitochondrial oxidative stress, and the role of the multidrug resistance proteins (MRP1) and lipid phosphate phosphatase(LPP) in regulating mitochondrial signaling under various pathological conditions. Dr. Panchatcharam has received many awards including scientist developmental grant award (National) and ATVB early career investigator awards from American Heart Association and NIH. He has authored research articles in Cir Res, ATVB, JBC and other prestigious journals, and book chapters for Springer and Humana Press. He has US patents in enzyme biotechnology. He has regularly served American Heart Association Study section and member of several national and international societies and associations (AHA, ADA, ISHR, NAVBO). Dr. Panchatcharam served as a reviver for several journals like AJP– heart and circulatory physiology; Biochemical Pharmacology; Vascular Pharmacology and servers as editorial board member for Research Journal in Pharmaceutical Sciences.

Cardiovascular Physiology, Coronary Artery Disease, Peripheral Vascular Disease, Clinical Outcomes Research.

Dr. Alexander E. Berezin has received PhD in 1994 in the State Medical University of Zaporozhye (Ukraine). He is currently working as a Professor of Medicine in the State Medical University of Zaporozhye (Ukraine). As a Chief of Cardiology Unit of Internal Medicine Department, his research goals are fundamental study of biological markers, the implementation of visualization procedures and percutaneous cardiovascular interventions, the development of cardiovascular prevention and rehabilitation, especially in the field affected heart failure, atherosclerosis, and coronary artery disease. Based on this research and training in heart failure he has received several awards and honors, such as: Award of The Cabinet of Ministersof Ukraine (2002), Honor of The Ukrainian Cardiology Association (2004), and is serving one of the active members of the European Cardiology Society. He has authored more 550 research articles, 15books/chapters. He is a fellow of the Ukrainian Cardiology Association; Member of the Ukrainian Heart Failure Association; Member of Heart Failure Association of the ESC; Member of European Acute Cardiovascular Care Association; Member of W.G. on Atherosclerosis and Vascular Biology of the ESC; Member of European Association of Percutaneous Cardiovascular Interventions; Member of European Association for Cardiovascular Prevention and Rehabilitation, Member of W.G. on Hypertension & the Heart of the ESC. He is current Editor-in-Chief of Biological Markers and Guided Therapy. He is serving as an editorial member of several reputed journals like Ukranian Medical J, J Cardiology and Therapy, Case Reports in Internal Medicine and expert Reviewers for journals like J Genetic Disorders and Genetic Reports; Obesity; Eur. J Clinical Investigations,etc.

Coronary Artery Disease, Heart Failure, Atherosclerosis Hypertension, Prognosis, Biological Markers, Genetic Markers, Comorbidities, Metabolic Disorders, Visualization Procedures, Cardiovascular Prevention and Rehabilitation, and Vascular Biology, Translation Medicine, Stem Cells.

Garth Graham, MD, MPH, is board certified in internal medicine and cardiology and previously served as deputy assistant secretary in the U.S. Department of Health and Human Services and assistant dean for health policy and chief of health services research at the University of Florida. Dr. Graham holds a MD and a MPH from Yale University and did his medicine training at Massachusetts General Hospital and cardiology training at Johns Hopkins.

Population Health Management of Cardiovascular Disease, Post PCI Risk Factor Modification and Health Disparities.

Professor Osmar Antonio Centurion, is a cardiologist with expertise in Coronary Heart Diseases and Arrhythmias, Hemodynamics and Electrophysiology and Arrhythmia Ablation. He is Professor of Medicine at the School of Medical Sciences from the Asuncion National University in Asunción, Paraguay. He received is PhD degree in Cardiology, at the Nagasaki University School of Medicine, Nagasaki, Japan in 1994. He is the Founding Member of Sociedad Latinoamericana de Cardiología Intervencionista (SOLACI). Author of more than 100 medical articles published in peer-reviewed American, European and Japanese journals in cardiology. His biography is published in "Who is Who in the World", "Who is Who in Science and Engineering", "Man of Achievement", "Who is who in Medicine and Healthcare". He is a Fellow of the American College of Cardiology, European Society of Cardiology, American Society of Angiology, and member of other 10 International Cardiovascular Societies. He is currently Chief of the Department of Cardiology, Hospital de Clinicas, Asunción, Paraguay.

Coronary Heart Diseases, Arrhythmias, Hemodynamics, Electrophysiology and Arrhythmia Ablation.

I have had a steadfast interest in cell signaling regulation since my formal scientific training as a doctoral student.   My thesis work focused on deciphering the various Toll-like receptor (TLR) mediated signaling pathways involved in host innate immune response to diseases like tuberculosis caused by Mycobacterium tuberculosis and H.pylori induced gastritis. I have always been very passionate and dedicated towards exciting scientific discovery. As part of my postdoctoral research for last five years, I have explored novel vasoregulatory roles for Notch signaling in vascular smooth muscles (VSM). Arterial vasoreactivity is a major determinant of circulatory blood flow and pressure regulation and relies on coordinated control of vascular tone by both vascular endothelial cells and VSM. We demonstrated pan-Notch receptor inhibition in VSM significantly impaired vasoreactivity and pressor responses in vivo and discovered that Notch signaling control the major regulatory contractile protein, myosin light chain kinase that catalyzes myosin light chain phosphorylation, the molecular signature of force production for the first time. Our recent work is suggestive of Notch ligand specific interaction of arterial contractility and relaxation.Data provide rationale for pursuing pharmacological strategies for blood pressure control through manipulation of vascular Notch signaling. We have recently extended our studies to understand the Notch-signaling pathway in VSMs challenged to hypoxic insult. It is known that in the vasculature, endothelial cell HIF is essential for physiological development, angiogenesis and hematopoiesis. Our preliminary studies reveal that Notch-HIF interactions exist in SM and functionally synergize to promote optimal angiogenesis.

Cardiovascular Research, Cardiovascular disease: Peripheral Hypertension, Vascular biology: Smooth muscle cell physiology, Notch signaling in vascular development and vasocontractility, Hypoxia in vascular smooth muscle cells.

Dr. Adigopula is an Advanced Heart Failure Cardiologist, Director of Heart Failure at Regional Medical Center and Assistant Professor in the Division of Cardiology at Loma Linda University. He completed his training at Stanford University and University of California at Los Angeles. He has authored many important papers and book chapters. He has published in prestigious medical journals including New England Journal of Medicine, Journal of the American College of Cardiology, Circulation, American Heart Journal, American Journal of Cardiology, Journal of American Society of Echocardiography and International Journal of Cardiovascular Imaging. He has received many national and international awards, recognition and grants for his clinical and research work. He has presented his research in many national and international Cardiology conferences. He serves on the Editorial board of many peer-reviewed medical journals. He is dedicated to academics, teaching, patient care, research in advance heart failure and advancement in medicine. He is a member of American Heart Association, American College of Cardiology, International Society for Heart and Lung Transplantation, American Society of Echocardiography, Heart Failure Society of America, American Society of Nuclear Medicine and American Medical Association. He is a Fellow in the American College of Cardiology and the American College of Physicians. His research interest includes stem cell therapy in heart failure and clinical outcomes in advanced heart failure. His personal interests include piano, tennis and soccer but most importantly spending time with his young children. In his spare time, he volunteers in a free medical clinic and promotes charitable organizations such as UNICEF and Red Cross. His research interests include stem cell therapy in Heart Failure, clinical outcomes in Advanced Heart Failure and Immunology in Heart Transplantation.

 

Advanced Heart Failure Clinical Outcomes, Stem Cell Therapy in Heart Failure, Mechanical Circulatory Support, Heart Transplantation, Cardiovascular Imaging.