Short communication Open Access
Lymphoma of the Liver in a Developing Community
Wilson IB Onuigbo*
Department of Pathology, The Medical Foundation & Clinic, 8 Nsukka Lane, Enugu 400001, Nigeria
*Corresponding author: Department of Pathology, The Medical Foundation & Clinic, 8 Nsukka Lane, Enugu 400001, Nigeria, Tel: +2348037208680, E-mail: @
Received: 1 March, 2018; Accepted: 11 June, 2018; Published: 18 June, 2018
Citation: Onuigbo WIB (2018) Lymphoma of the Liver in a Developing Community. J Hepatol Gallblader Dis Research 2(1): 1-2.
Literature search revealed lymphoma of the liver in various countries as regards single or more cases. These data are compared with those obtained from patients of the Igbo ethnic group in Nigeria. As in different parts of the world, males were affected more often than females.

Keywords: Liver; lymphoma; sex; developing community.
Internet search regarding lymphoma of the liver revealed single cases from countries as variegated as India, Uruguay, Greece, and USA [1- 4]. Therefore, since the Birmingham (UK) group emphasized that the establishment of a histopathology data pool improves epidemiological analysis, this paper is based on such a pool used by the Igbo ethnic group [5, 6]. It was pioneered personally from 1970. So far, regarding the lymphoma broadly, other articles pertained to the breast, the forensic presentation and the palate [7-9]. Meanwhile, there have been other coauthored papers on the small bowel, bilateral breast and vagina [10-12].
The Government of the Eastern Region of Nigeria established a Regional Reference Laboratory at Enugu, the capital city. As the pioneer pathologist, I insisted on biopsy specimens being submitted in formol-saline with epidemiological data. The cases which I diagnosed as lymphoma of the liver are the subject of this paper. They are presented in tabular form.
Table 1: The epidemiological data






Provisional Diagnosis





Abdominal pain






Abdominal mass






Abdominal mass






Abdominal distension






Abdominal swelling






Abdominal pain


Comparison with the world pattern is indicated. Surprisingly, this was not clear in the monograph on malignant lymphoma. Thus, the liver was not indexed [13].

In a series of 3 patients from Brazil, all were males in the fifth decade of life [14]. The local series is comparable in the sense that males preponderated and the mean age was 42 years. Similarly, middle aged males were most often affected in Hong Kong [15]. Indeed, considering the worldwide epidemiology of adult lymphoma, Boffetta found its occurrence to be higher in men than in women [16].

Most patients had abdominal pain with hepatomegaly in a USA paper [17]. The Igbo patients showed this pattern.

Another USA paper suggested that liver lymphomas exhibit two types, namely, nodular and diffuse [18]. It was not possible to ascertain this segregation with the local biopsy specimens.
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  7. Onuigbo WIB. Lymphoma of breast in a developing community. Cancer Therap Oncol Intl J. 2018;8(5):CTOIJ.MS.ID.555746.
  8. Onuigbo WIB. Forensic presentations of malignant lymphoma in Nigeria. Forensic Sci Addict Res. 2018;2(suppl-1). DOI: 10.31031/ FSAR.2018.02.000533
  9. Onuigbo WIB. The palate: Malignant lymphoma. Glob J Otolaryngol. 2018;15(2):GJO.MS.ID.555906.
  10. Onuigbo WIB, Nze PU. Small bowel lymphoma coupled with incidental appendectomy in a developing community. Cancer Therap Oncol Intl J. 2018;8(5):CTOIJ.MS.ID.555743.
  11. Onuigbo WIB, Anyaeze C, Molloy M, Kalk A. Bilateral breast lymphoma in a developing community. Glob J Reprod Med. 2018;4(1): GJORM.MS.ID.555628.
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