Editorial
Open Access
A Review on Articles in the Current Issue
Hsuan-Hsiang Chen*
Department of Dermatology, National Taiwan University Hospital, Chung-Shan South Road, Taipei, Taiwan
*Corresponding author: Hsuan-Hsiang Chen, Department of Dermatology, National Taiwan University Hospital, 7, Chung-Shan South Road, Taipei,
Taiwan, Tel: +886-2-2356-2141; Fax: +886-2-2393-4177; E-mail:
@
Received: December 29, 2015; Accepted: December 30, 2015; Published: December 31, 2015
Citation: Chen HH (2016) A Review on Articles in the Current Issue. Clin Res Dermatol Open Access 2(2): 1-2. DOI: http://dx.doi.org/10.15226/2378-1726/2/2/00126
One of the most exciting and fascinating features in
Dermatology is the various presentation of color, distribution,
morphology, pattern, and clinical course of the skin lesions. In
this coming issue, we launched two new article types: Clinical
and medical images and Therapeutic Hotline Letters. We
hope through these two new sections, the journal will become
more successful and inspiring than ever.
In the Clinical and medical images section, Bakardzhiev I, et al [1] reminds us the unusual presentation of serial multiple genital ulceration of ulcus durum may be considered super infection or re-infection of primary syphilis in patients with repeated and indiscriminate casual unprotected sexual contacts.
In the Therapeutic Hotline Letters section, Tchernev G et al [2] presented a case with huge "Shuriken-like "superficial spreading malignant melanoma without locoregional metastasis. They speculated that congenital or acquired defects in T-cell immunity with the persistence or delayed elimination of certain T-cell clones, similar to the effect of current target therapies PD-1 receptor and CTLA-4 inhibitors, may explain the lack of progression in certain giant melanoma.
Finally, Persechino S et al [3] showed the safety of etanercept administration to a patient with psoriasis, concomitant HCV infection, mild liver disease, and signs of previous contact with HBV. Since the biological therapy is becoming the standard treatment for psoriasis and psoriatic arthropathy, more data on anti-TNFα drug safety in active HCV patients with concomitant previous HBV contact are mandatory.
In the Clinical and medical images section, Bakardzhiev I, et al [1] reminds us the unusual presentation of serial multiple genital ulceration of ulcus durum may be considered super infection or re-infection of primary syphilis in patients with repeated and indiscriminate casual unprotected sexual contacts.
In the Therapeutic Hotline Letters section, Tchernev G et al [2] presented a case with huge "Shuriken-like "superficial spreading malignant melanoma without locoregional metastasis. They speculated that congenital or acquired defects in T-cell immunity with the persistence or delayed elimination of certain T-cell clones, similar to the effect of current target therapies PD-1 receptor and CTLA-4 inhibitors, may explain the lack of progression in certain giant melanoma.
Finally, Persechino S et al [3] showed the safety of etanercept administration to a patient with psoriasis, concomitant HCV infection, mild liver disease, and signs of previous contact with HBV. Since the biological therapy is becoming the standard treatment for psoriasis and psoriatic arthropathy, more data on anti-TNFα drug safety in active HCV patients with concomitant previous HBV contact are mandatory.
- Bakardzhiev I, Pehlivanov G, Chokoeva AA, Tchernev G. Syphilis Primaria Seropositiva : A "Clinical Chameleon:"? Clin Res Dermatol Open Access. 2015;2(2):1-2.
- Tchernev G, Chokoeva AA. A "Shuriken-like" Pigmented Lesion? Clin Res Dermatol Open Access. 2015;2(2):1-2.
- Persechino S, Pigliacelli F, Merola E, Persechino F, Signoretti M, Marignani M, Tammaro A. Safety and Efficacy of Etanercept in a HCV/ HBV Patient Affected by Psoriasis. Clin Res Dermatol Open Access. 2015;2(2):1-2.
