During my active involvement in Virology and Retrovirology for more than fifty years , I went through different phase of study with various viruses. They include poxviruses, paramyxoviruses, or rhabdoviruses. Each of these families of viruses taught me a new lesson and the most attractive virus family for me – retroviruses. Therefore, the idea to connect general virology with retrovirology is close to my heart. Both these fields have a series of interconnections when seen from the point of constructing suitable vectors which are required for the transmission of genetic information. We are also gaining better insight into the cellular functions and the lack of which or activation of which keep in check the outcome of virus infection. Potentially other viruses constitute an important part of human and animal genomes and can provide new functions, such as triggering syncytiotrophoblast formation which will open new ways to express some of the genes through splicing signals. Speaking about retroviruses I should underline the significance of retroelements and sequences amplified by reverse transcription, which together constitute the majority of our DNA genome. Needless to say, we are at the beginning of understanding the significance of these processes for our genome shaping and functionality. I believe that this new virology and retrovirology journal will provide a thorough understanding of retrovirus research and also it is ideally suitable for spreading cutting edge information to large public very rapidly.